Harley quinn
The character, a supervillain, later an antihero in the DC Comics universe, originally appeared in 1992's Batman, was later carried over into comics. She is the main associate of the Joker, for the same reason she hates Batman and his assistants. Also maintains friendships with Poison Ivy and Catwoman. The character's nickname is derived from her real name, Harlene Quinzel, as an association with the word "harlequin".
